ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ig kappa chain V-III region PC 3741/TEPC 111

Intramolecular
Cysteine 23 and cysteine 92
A redox-regulated disulphide may form within Ig kappa chain V-III region PC 3741/TEPC 111 between cysteines 23 and 92 (23 and 88 respectively in this structure).

Details

Redox score ?
78
PDB code
1j05
Structure name
the crystal structure of anti-carcinoembryonic antigen monoclonal antibody t84
Structure deposition date
2002-11-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
96
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01660
Residue number A
23
Residue number B
92
Peptide name
Ig kappa chain V-III region PC 3741/TEPC 111

Ligandability

Cysteine 23 of Ig kappa chain V-III region PC 3741/TEPC 111

Cysteine 92 of Ig kappa chain V-III region PC 3741/TEPC 111

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